X. Chen, Y. Wu, C. Chen, Y. Gu, C. Zhu, S. Wang, J. Chen, L. Zhang, L. Lv, G. Zhang, Y. Yuan, Y. Chai, M. Zhu, C. Wu. Identifying potential anti-COVID-19 pharmacological components of traditional Chinese medicine Lianhuaqingwen based on human exposure and ACE2 biochromatography screening. Acta Pharmaceutica Sinica B, 2021 Jan;11(1):222-236.

T. Cai, C. Wu, Q. Ruan, S. Ma, M. Zhu. High-resolution mass spectrometry-based data acquisition and data mining technologies for detecting and characterizing drug metabolites and herbal medicine components. In Identification and Quantification of Drugs, Metabolites, Drug Metabolizing Enzymes, and Transporters (Second Edition); Concepts, Methods, and Translational Sciences, 2020, Pages 73-117.

Diao X, Carlier J, Zhu M, Huestis MA (2018). Metabolism of the new synthetic cannabinoid EG-018 in human hepatocytes by high-resolution mass spectrometry. Forensic Toxicol, 36:304-312.

J. Pu, F. Wang, W. Tang, M. Zhu. Biotransformation of ilaprazole in human liver microsomes and human: role of CYP3A4 in ilaprazole clearance and drug-drug interaction. Drug Metab Dispos. 46(10):1453-1461. 2018.

Diao X#, Carlier J#, Zhu M, Huestis MA (2017). Human hepatocyte metabolism of novel synthetic cannabinoids MN-18 and its 5-fluoro analog 5F-MN-18. Clin Chem, 63: 1753-1763.

Diao X#, Carlier J#, Scheidweiler KB, Huestis MA (2017). In vitro metabolism of new synthetic cannabinoid SDB-006 in human hepatocytes by high-resolution mass spectrometry. Forensic Toxicol, 35: 252-262.

Carlier J#, Diao X#, Sempio C, Baumann MH, Huestis MA (2017) Identification of new synthetic cannabinoid ADB-CHMINACA (MAB-CHMINACA) metabolites in human hepatocytes. AAPS J, 19: 568-577. 

Diao X, Carlier J, Zhu M, Pang S, Kronstrand R, Scheidweiler KB, Huestis MA (2017). In vitro and in vivo human metabolism of a new synthetic cannabinoid NM-2201 (CBL-2201). Forensic Toxicol, 35: 20-32.

Carlier J, Diao X, Wohlfarth A, Scheidweiler KB, Huestis MA (2017). In vitro metabolite profiling of ADB-FUBINACA, a new synthetic cannabinoid. Curr Neuropharmacol, 15: 682-691.

Diao X, Scheidweiler KB, Wohlfarth A, Zhu M, Pang S, Huestis MA (2016). Strategies to distinguish new synthetic cannabinoid FUBIMINA (BIM-2201) intake from its isomer THJ-2201: metabolism of FUBIMINA in human hepatocytes. Forensic Toxicol, 34: 256-267.

 Xiao W, Shen G, Zhuang X, Ran X, Zhu M, Li H. Characterization of human metabolism and disposition of levo-tetrahydropalmatine: Qualitative and quantitative determination of oxidative and conjugated metabolites. J Pharm Biomed Anal. 5;128:371-81. 2016.

Andersson M, Diao X, Wohlfarth A, Scheidweiler KB, Huestis MA (2016). Metabolic profiling of new synthetic cannabinoids AMB and 5F-AMB by human hepatocyte and liver microsome incubations and high-resolution mass spectrometry. Rapid Commun Mass Spectrom, 30: 1067-1078.

Diao X, Scheidweiler KB, Wohlfarth A, Pang S, Kronstrand R, Huestis MA (2016). In vitro and in vivo human metabolism of synthetic cannabinoids FDU-PB-22 and FUB-PB-22. AAPS J, 18: 455-464.

Diao X, Wohlfarth A, Pang S, Scheidweiler KB, Huestis MA (2016). High-resolution mass spectrometry for characterizing the metabolism of synthetic cannabinoids THJ-018 and its 5-fluoro analog THJ-2201 after incubation in human hepatocytes. Clin Chem, 62: 157-169.

Xiao W, Shen G, Zhuang X, Ran X, Zhu M, Li H. Characterization of human metabolism and disposition of levo-tetrahydropalmatine: Qualitative and quantitative determination of oxidative and conjugated metabolites. J Pharm Biomed Anal. 5;128:371-81. 2016

Xing J, Zang M, Zhang H, Zhu M. The application of high-resolution mass spectrometry-based data-mining tools in tandem to metabolite profiling of a triple drug combination in humans. Anal Chim Acta. 15;897:34-44. 2015.

H. Zhang and M. Zhu. Drug metabolite identification with high resolution mass spectrometry. Editors, Philip W Lee, Hiroyasu Aizawa, Lawrence L Gan, Chandra Prakash and Defang Zhong. Handbook of Metabolic Pathways of Xenobiotics. John Wiley & Sons, 2013.

Gandhi AS, Zhu M, Pang S, Wohlfarth A, Scheidweiler KB, Liu HF, Huestis MA. First Characterization of AKB-48 Metabolism, a Novel Synthetic Cannabinoid, Using Human Hepatocytes and High-Resolution Mass Spectrometry. AAPS J. 15(4):1091-8, 2013.

F. Du, Q. Ruan, M. Zhu, and J. Xing. Detection and characterization of ticlopidine conjugates in rat bile using high resolution mass spectrometry: applications of various data acquisition and processing tools. J Mass Spectrom. J Mass Spectrom. 48(3):413-22, 2013.

Cyanide Adducts Using Precursor Ion and Neutral Loss Scans-dependent Product Ion Spectral Acquisition and Data Mining Tools. J Am Soc Mass Spectrom. 23(5):964. 2012.

Ruan Q, Zhu M. Investigation of bioactivation of ticlopidine using linear ion trap/orbitrap mass spectrometry and an improved mass defect filtering technique. Chem Res Toxicol.  17;23(5):909-17. 2010.

H. Zhang, D. Zhang, K. Ray and M. Zhu. Mass defect filter technique and its applications to drug metabolite identification by high-resolution mass spectrometry. J Mass Spectrom. 44(7):999-1016. 2009.

S. Ma and M. Zhu. Recent advances in applications of liquid chromatography-tandem mass spectrometry to the analysis of reactive drug metabolites. Chemico-Biological Interactions, 179(1):25-37, 2009.

J. Gan, Q. Ruan, B. He, M. Zhu, W. Shyu, W. Humphreys. In vitro screening of 50 highly prescribed drugs for thilo addict formation - Comparison of potential for drug induced toxicity and extent of adduct formation. Chem. Res. Toxicol. 22(4):690-8, 2009.

X. Zhuo, W. Zhao, J. Zheng, Y. Shu, W. Humphreys, M. Zhu. Studies of rat olfactory P450-mediated bioactivation of xenobiotics: coumarin as a model compound. Chem Biol Interact. 181(2):227-35. 2009.

B. Wen, L. Ma, A. Rodrigues and M. Zhu. Detection of novel reactive metabolites of trazodone: evidence for CYP2D6-mediated bioactivation of m-chlorophenylpiperazine. Drug Metab Dispos. 36(5):841-850, 2008.

M. Yao, M.  Zhu, S. Chang, D. Zhang and A Rodrigues. Chapter 15. Applications of recombinant and purified human drug-metabolizing enzymes: an industrial perspective, in Handbook of Drug Metabolism”, 2nd Edition; Editors, L. C. Wienkers and P. G. Pearson. Taylor & Francis, Inc. November 2008.

B. Wen, L. Ma and M. Zhu. Bioactivation of the tricyclic antidepressant amitriptyline and its metabolite nortriptyline to arene oxide intermediates in human liver microsomes and recombinant P450s. Chemico-Biological Interactions. 173(1): 59-67, 2008.

Q. Ruan, S. Peterman, M. Szewc, L. Ma, D. Cui, W. Humphreys, M. Zhu. An integrated method for metabolite detection and identification using LTQ/Orbitrap mass spectrometry and multiple data processing techniques: application to indinavir metabolite detection. J Mass Spectrom. 43(2):251-261 2008.

H. Zhang, L. Ma, K. He, M. Zhu. Use of a background subtraction algorithm for detection of troglitazone metabolites in rat plasma, bile, and urine. J Mass Spectrom. 43(9):1191-1200, 2008.

B. Wen, L. Ma, S. Nelson, and M.  Zhu. High-throughput screening and characterization of reactive metabolites using polarity switching of hybrid triple quadrupole linear ion trap mass spectrometry. Anal Chem. 80: 1788-1799, 2008.

M. Yao, L. Ma, W. Humphreys, M. Zhu. Rapid metabolite screening and characterization of reactive metabolites using a multiple ion monitoring-dependent MS/MS acquisition method on a hybrid triple quadrupole-linear ion trap mass spectrometer. J Mass Spectrom. 43(10):1364-1375, 2008.

J. Zheng, L. Ma, Baomin Xin, T. Olah, W.  M.  Zhu. Screening and Identification of GSH-Trapped Reactive Metabolites Using Hybrid Triple Quadruple Linear Ion Trap Mass Spectrometry.  Chem Res Toxicol. 20(5):757-66, 2007.

M. Zhu, L. Ma, H.  Zhang and W. Humphreys. Detection and structural characterization of glutathione-trapped reactive metabolites using liquid chromatography-high resolution mass spectrometry and mass defect filtering. Anal. Chem. 79(21):8333-41, 2007.

D. Zhang, H. Zhang, N. Aranibar, R. Hanson, Y. Huang, P. Cheng, S. Wu, S. Bonacorsi, M. Zhu, A. Swaminathan, W. Humphreys.  Structural elucidation of human oxidative metabolites of muraglitazar: use of microbial bioreactors in the biosynthesis of metabolite standards.  Drug Metab Dispos. 34(2):267-80, 2006.

M. Zhu, L. Ma, D. Zhang, K. Ray, W. Zhao, W. Humphreys, G. Skiles, M. Sanders, H. Zhang. Detection and characterization of metabolites in biological matrices using mass defect filtering of liquid chromatography/high resolution mass spectrometry data. Drug Metab Dispos. 34(10):1722-33, 2006.